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Energy Ignite

Does not Contain
Wheat, gluten, yeast, soy protein, animal and dairy products, fish, shellfish, peanuts, tree nuts, egg, ingredients derived from genetically modified organisms (GMOs), artificial colors, artificial sweeteners, and artificial preservatives.

Energy Ignite

Energy Ignite transforms water into a great-tasting, revitalizing energy drink. Each stick provides a combination of B vitamins, electrolytes, trace minerals, amino acids, herbs, and antioxidants to fuel your body’s energy production. Building on these important nutrients, Energy Ignite also features caffeine pterostilbene co-crystal, a technology- driven, patent-protected ingredient that combines caffeine and pterostilbene. Initial reports suggest that caffeine pterostilbene co-crystal’s caffeine may be absorbed more slowly and stay in your system longer than regular caffeine, which may help your energy last longer. With just 5 g of carbohydrate per serving and zero sugars, Energy Ignite simply gives your body what it needs to produce energy.*

All R2 Medical Clinic Formulas Meet or Exceed cGMP Quality Standards


Caffeine Pterostilbene Co-Crystal
Caffeine pterostilbene co-crystal is an innovative ingredient that combines caffeine with pterostilbene—a highly bioavailable analog of resveratrol—to form a unique co-crystal structure. It appears that this unique structure affects the way the body utilizes caffeine. As such, it may offer significant advantages over caffeine alone.*

Study Findings
In a rat study (n=6), the half-life of the caffeine from caffeine pterostilbene co-crystal was eight hours, while that of ordinary caffeine was just three hours.[1] In a preliminary, four-week, single-blind, crossover human study (n=12) that compared 232 mg of caffeine pterostilbene co-crystal (providing 99.76 mg of caffeine) to 100 mg of ordinary caffeine, the following effects were demonstrated[2,3]:

  • Caffeinepterostilbeneco-crystal delivered almost 30% more caffeine into the blood than ordinary caffeine.*
  • The absorption rate of the caffeine from caffeinepterostilbeneco-crystal was significantly slower by approximately 30% compared to ordinary caffeine.*
  • The absorption rate of the caffeine from caffeinepterostilbeneco-crystal was significantly slower by approximately 30% compared to ordinary caffeine.
  • Thehalf-lifeofthecaffeinefromcaffeinepterostilbeneco-crystalwasextendedsignificantlybyapproximately25% comparedto ordinary caffeine.*
  • At4hours,serumshowed45%morecaffeinefromcaffeinepterostilbeneco-crystalcomparedtoordinarycaffeine.*
  • At6hours,serumshowed51%morecaffeinefromcaffeinepterostilbeneco-crystalcomparedtoordinarycaffeine.*
  • Caffeinepterostilbeneco-crystalhadnoadverseeffect.*
While the results of these studies are promising, larger studies are needed to validate the findings and determine if these findings translate into a lengthened energy effect.*

More Energy

Taken together, data from these studies suggest that the effects of caffeine from caffeine pterostilbene co-crystal may last longer than the effects from ordinary caffeine and point to a potential for reducing total caffeine intake due to caffeine pterostilbene co-crystal’s more efficient delivery and slower absorption rate. These are encouraging factors for people who wish to reduce their caffeine intake.* Slower Caffeine “Finish” Scientists are researching whether or not the extended half-life and slower absorption rate of caffeine from caffeine pterostilbene co-crystal can produce a more moderated and gradual finish. This may help prevent the “crash” associated with regular caffeinated energy products and may give Energy Ignite an advantage over formulas that use ordinary caffeine.*

All-Natural, No Sugars

Energy Ignite relies on natural ingredients, not ephedra or artificial stimulants. Furthermore, it provides only five grams of carbohydrates and zero sugars. By using natural flavors and stevia in place of sugar and other carbohydrates, the typical “sugar high” that is associated with many energy drinks can be avoided. Equally important, Energy Ignite contains no artificial colors.*
Caffeine, in General
In animal and human studies, caffeine has demonstrated positive effects on athletic performance, fatigue, and cognitive functions, such as supporting a healthy memory.[4-8] According to Meeusen et al, research on caffeine suggests its performance-enhancing effect is related to antagonism of the adenosine receptors that influence the dopaminergic and other neurotransmitter systems.*[9]


In the aforementioned human study, caffeine pterostilbene co-crystal also delivered approximately 50% more total pterostilbene into the blood than pterostilbene delivered alone,[2] thus potentially enhancing the functional benefits of pterostilbene. Pterostilbene is a highly bioavailable analog of resveratrol—a stilbenoid found in blueberries and grapes. Compared to resveratrol, pterostilbene is four times more bioavailable,[10] has a seven times greater half-life,[11] exhibits greater oral absorption and metabolic stability (pterostilbene is more lipophilic), and produces two to four times greater cellular uptake.[12] Aside from resveratrol’s well-known antioxidant benefits that support cardiovascular health, pterostilbene is also known to activate certain proteins (i.e., SIRT1 and PGC-1α) involved in increasing mitochondrial biogenesis and therefore ATP (energy) production.*[13-15]

Electrolytes and Antioxidants

Electrolytes—including sodium, potassium, and magnesium—are important for energy production, nerve transmission, muscle contractions, pH balance, fluid balance, and more. Conditions that promote excessive sweating and increased metabolic activity can require replacement of these important minerals and increase the need for antioxidants. Energy Ignite provides 130 mg of sodium, 280 mg of potassium, and 150 mg of magnesium in each serving. To support protection from free radicals, Energy Ignite provides 500 mg of vitamin C in the form of four mineral ascorbates, as well as natural vitamin E, selenium, green tea extract, and s-acetyl-L-glutathione (SAG). SAG is an orally stable glutathione that has been shown to cross the membrane of the mitochondria, which increases the organelle’s activity and helps minimize reactive oxygen species.*

Herbs and Amino Acids

Energy Ignite combines caffeine pterostilbene co-crystal in a proprietary blend with various herbs and amino acids, including green tea extract, coffee fruit extract, taurine, and L-arginine alpha-ketoglutarate. This proprietary blend is designed to complement the activities of caffeine pterostilbene co-crystal. Furthermore, some of these individual ingredients taken in high doses have roles in mitochondrial biogenesis or are known to have a positive influence on exercise performance.*[16-18]

B Vitamins

As essential parts of coenzymes, these water-soluble nutrients are integral to the complex biochemical processes that convert food to glucose and ATP—the energy used by cells. Vitamin B12 also works closely with folate to help make red blood cells and facilitate the work of iron in the body. Iron helps carry oxygen to all cells, including muscle cells, for use in the generation of energy.*
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