InMode ApexRF for ED: Non-Invasive Treatment
InMode ApexRF treats erectile dysfunction without pills, needles, or surgery using RF energy and EMS therapy. Free consult at R2 Medical Denver.
R2 Medical Clinic • 2026-03-01T23:55:55.046716+00:00 • 11 min read
Medically Reviewed By: Dr. Erik Natkin, DO — Founder, R2 Medical Clinic
Key Takeaways
- InMode ApexRF is an FDA-cleared device that combines radiofrequency (RF) energy with functional electrical muscle stimulation (EMS) to treat erectile dysfunction at its physiological source.
- The treatment is completely non-invasive: no surgery, no needles, no medication, and zero downtime.
- A standard protocol involves 6 sessions over 3 consecutive weeks (twice per week), with each session lasting only 15 to 20 minutes.
- ApexRF promotes actual tissue healing through collagen production, neovascularization (new blood vessel growth), and pelvic floor muscle strengthening.
- The treatment can be combined with PRP (P-Shot), testosterone replacement therapy (TRT), and other modalities for maximum results.
Why Erectile Dysfunction Deserves a Better Solution
Erectile dysfunction affects an estimated 30 million men in the United States alone. Despite how common it is, most men feel limited to two options: take a pill or live with it. Neither approach addresses the underlying cause.
At R2 Medical Clinic in Denver, Dr. Erik Natkin, DO, offers a fundamentally different approach. With board-level training in orthopedic surgery, pain management, and regenerative medicine, Dr. Natkin focuses on treatments that restore function rather than mask symptoms. InMode ApexRF represents exactly that philosophy: a treatment that targets the physiological root of erectile dysfunction and promotes genuine tissue repair.
ED is not simply a psychological issue. In most cases, it stems from reduced blood flow, weakened smooth muscle tissue, decreased collagen integrity, and pelvic floor dysfunction. These are structural and vascular problems that require structural and vascular solutions.
What Is InMode ApexRF?
InMode ApexRF is an FDA-cleared medical device designed specifically for men's intimate wellness. It uses a dual-mechanism approach that sets it apart from every other ED treatment on the market.
The device combines two proven therapeutic technologies into a single treatment session:
Radiofrequency (RF) Energy
Controlled RF energy penetrates the targeted tissue, generating therapeutic heat at precise depths. This thermal stimulation triggers the body's natural healing response, producing three critical outcomes:
Collagen remodeling and production. Existing collagen fibers contract and tighten while new collagen synthesis begins. This restores structural integrity to penile tissue that has degraded over time.
Neovascularization. The RF energy stimulates angiogenesis, the formation of new blood vessels. Improved vascular density means increased blood flow, which is the single most important factor in erectile quality.
Cellular regeneration. Heat-activated growth factors promote repair at the cellular level, reversing age-related and disease-related tissue degradation.
Functional Electrical Muscle Stimulation (EMS)
Simultaneously, the ApexRF device delivers targeted electrical impulses to the pelvic floor muscles. The pelvic floor plays a critical but overlooked role in erectile function:
The bulbocavernosus and ischiocavernosus muscles are directly responsible for maintaining rigidity during erection. When these muscles weaken, erectile quality declines regardless of blood flow.
EMS strengthens these muscles through involuntary contraction cycles that are far more effective than voluntary exercises alone.
Improved pelvic floor tone also benefits urinary continence, another common concern for men as they age.
This dual-mechanism approach means ApexRF addresses ED from both the vascular side (blood flow and tissue quality) and the muscular side (pelvic floor strength and control). No other single treatment does both.
How the ApexRF Treatment Protocol Works
The standard ApexRF protocol at R2 Medical Clinic follows a structured, evidence-based schedule:
Treatment Schedule
- 6 total sessions over 3 consecutive weeks
- 2 sessions per week, spaced evenly
- 15 to 20 minutes per session
- No preparation required before each session
- No recovery time after each session
What to Expect During a Session
Each session takes place in a private treatment room at R2 Medical Clinic. The process is straightforward:
- Positioning. You are seated comfortably. No undressing below the waist is necessary for most of the treatment.
- Application. The ApexRF applicator is placed externally on the treatment area. The device delivers RF energy and EMS simultaneously.
- Sensation. Most patients describe a warm sensation from the RF energy and a mild tingling or pulsing from the EMS. The treatment is not painful.
- Completion. After 15 to 20 minutes, the session is complete. You can immediately return to work, exercise, or any normal activity.
There is genuinely zero downtime. Patients at our Denver clinic routinely schedule ApexRF sessions during lunch breaks and return to work immediately afterward.
When Results Appear
Many men notice initial improvements after the first two to three sessions. Optimal results typically develop over the full treatment course and continue to improve for several weeks after the final session as new collagen matures and blood vessel growth stabilizes.
ApexRF vs. Other ED Treatments: Complete Comparison
One of the most common questions we hear at R2 Medical Clinic is how ApexRF compares to other available ED treatments. Here is a direct comparison:
| Feature | InMode ApexRF | P-Shot (PRP) | Shockwave Therapy | Medications (PDE5 Inhibitors) |
|---|---|---|---|---|
| Mechanism | RF energy + EMS | Platelet-rich plasma injection | Acoustic sound waves | Phosphodiesterase inhibition |
| Invasiveness | Non-invasive (external) | Minimally invasive (injection) | Non-invasive (external) | Oral medication |
| Needles Required | No | Yes | No | No |
| Downtime | None | Minimal (24–48 hours) | None | N/A |
| Addresses Root Cause | Yes (tissue + muscle) | Yes (tissue regeneration) | Yes (vascular) | No (symptom management) |
| Sessions Required | 6 sessions over 3 weeks | 1–3 sessions | 6–12 sessions | Ongoing (per use) |
| Session Duration | 15–20 minutes | 30–45 minutes | 20–30 minutes | N/A |
| Pain Level | None | Mild (numbing applied) | Mild discomfort | N/A |
| Long-Term Results | Yes | Yes | Yes | No (effect wears off) |
| Drug-Free | Yes | Yes | Yes | No |
| Builds New Blood Vessels | Yes | Yes | Yes | No |
| Strengthens Pelvic Floor | Yes | No | No | No |
| Combinable with Other Therapies | Yes | Yes | Yes | Limited |
Key Distinctions
ApexRF vs. Medications. PDE5 inhibitors like sildenafil and tadalafil work by temporarily increasing blood flow during arousal. They do not repair tissue, build new blood vessels, or strengthen muscles. When the medication wears off, so does the effect. ApexRF promotes lasting structural changes. Many men who have relied on medications find that ApexRF reduces or eliminates their need for pills.
ApexRF vs. P-Shot. The P-Shot (Priapus Shot) uses platelet-rich plasma injections to stimulate tissue regeneration. It is effective but does involve a needle and a brief recovery period. ApexRF achieves tissue regeneration through external RF energy with no needles whatsoever. At R2 Medical Clinic, we frequently combine both treatments for patients who want maximum benefit.
ApexRF vs. Shockwave Therapy. Acoustic wave therapy uses sound waves to stimulate blood vessel growth. It addresses the vascular component of ED effectively but does not strengthen pelvic floor muscles. ApexRF addresses both vascular and muscular factors simultaneously.
Who Is a Good Candidate for ApexRF?
ApexRF is appropriate for a wide range of men experiencing erectile dysfunction. Ideal candidates include men who:
- Experience mild to moderate ED and want to avoid medication
- Currently use ED medications and want to reduce or eliminate dependence
- Have not responded adequately to medications alone
- Want to maintain erectile function proactively as they age
- Prefer a completely non-invasive, needle-free treatment
- Have pelvic floor weakness contributing to erectile or urinary issues
- Want to combine treatments for a comprehensive approach
During your consultation at R2 Medical Clinic, Dr. Natkin or Allison Wright, FNP-C, will evaluate your medical history, current symptoms, and treatment goals to determine whether ApexRF is the right fit, either as a standalone treatment or as part of a multi-modal protocol.
Combining ApexRF with Other Treatments
One of the greatest advantages of ApexRF is its compatibility with other therapies. At R2 Medical Clinic, we regularly design combination protocols that address ED from multiple angles:
ApexRF + P-Shot
Combining RF/EMS therapy with PRP injections creates a synergistic effect. ApexRF builds new blood vessels and strengthens pelvic floor muscles while the P-Shot delivers concentrated growth factors directly into penile tissue. Together, they accelerate tissue regeneration beyond what either treatment achieves alone.
ApexRF + Testosterone Replacement Therapy (TRT)
Low testosterone is a contributing factor in many cases of ED. When hormone levels are optimized through TRT and tissue health is restored through ApexRF, the results are often dramatically better than either treatment in isolation.
ApexRF + Lifestyle Optimization
Dr. Natkin emphasizes that no treatment works in a vacuum. Cardiovascular health, sleep quality, stress management, and body composition all influence erectile function. ApexRF combined with targeted lifestyle modifications produces the most durable, long-term improvements.
R2 Medical Clinic's Approach to Men's Sexual Health
ED treatment at R2 Medical Clinic is not transactional. Dr. Erik Natkin brings a regenerative medicine perspective to every case, drawing on his training in orthopedic surgery and pain management to identify and address the underlying cause of dysfunction rather than simply prescribing a pill.
Every patient receives a thorough evaluation that considers hormonal status, vascular health, pelvic floor function, and overall wellness. Treatment plans are individualized. For some men, ApexRF alone is sufficient. For others, a combination approach delivers optimal results.
Our Denver location at 1873 S Bellaire St, Suite 1215, serves patients from across the metro area, including Arvada, Wheatridge, Castle Rock, and surrounding communities. We also maintain clinic locations in Arvada-Wheatridge and Castle Rock for convenience.
Frequently Asked Questions
How much does InMode ApexRF treatment cost?
ApexRF pricing varies based on the treatment plan recommended during your consultation. R2 Medical Clinic offers transparent pricing and flexible payment options. Because ApexRF addresses the root cause of ED rather than providing temporary symptom relief, many patients find it more cost-effective than a lifetime of medication. Call (720) 640-2333 for current pricing.
Is ApexRF painful?
No. ApexRF is consistently described as comfortable by patients at R2 Medical Clinic. You will feel a warm sensation from the radiofrequency energy and a mild pulsing from the electrical muscle stimulation. Neither sensation is painful. No anesthesia or numbing is required.
How many sessions do I need?
The standard protocol is 6 sessions, performed twice per week over 3 consecutive weeks. Each session lasts 15 to 20 minutes. Some patients may benefit from maintenance sessions after the initial protocol, which Dr. Natkin will discuss during your follow-up evaluation.
Who is a good candidate for ApexRF?
Most men experiencing erectile dysfunction are candidates for ApexRF. It is particularly well suited for men who want a non-invasive, drug-free option; men who want to reduce reliance on ED medications; and men who want to address pelvic floor weakness alongside vascular issues. A consultation with Dr. Natkin or Allison Wright, FNP-C, will confirm whether ApexRF is appropriate for your specific situation.
Can ApexRF be combined with other ED treatments?
Yes. ApexRF is frequently combined with the P-Shot (PRP therapy), testosterone replacement therapy, and other treatments at R2 Medical Clinic. Combining modalities often produces superior results because each therapy targets a different aspect of erectile function. Dr. Natkin designs individualized combination protocols based on each patient's needs.
How long do ApexRF results last?
Results from ApexRF are durable because the treatment promotes actual structural changes: new collagen, new blood vessels, and stronger pelvic floor muscles. Many patients experience sustained improvement for 12 months or longer. Periodic maintenance sessions can extend and reinforce results over time. Individual outcomes vary based on overall health, lifestyle factors, and the severity of the initial dysfunction.
Why Choose R2 Medical Clinic for ED Treatment
R2 Medical Clinic stands apart because we treat erectile dysfunction as a medical condition with identifiable causes and measurable solutions. Dr. Erik Natkin, DO, brings extensive training in orthopedic surgery, pain management, and regenerative medicine to every patient interaction. Our team, including Allison Wright, FNP-C, is committed to evidence-based treatments that restore function rather than mask symptoms.
We offer InMode ApexRF alongside a full spectrum of men's health therapies, including the P-Shot, testosterone replacement therapy, and peptide protocols, all under one roof at our Denver clinic. This integrated approach means your treatment plan is coordinated, comprehensive, and designed for lasting results.
Ready to treat ED at its source? Schedule your free consultation. Call (720) 640-2333 or visit r2medicalclinic.com.
Dr. Erik Natkin, DO — Founder, R2 Medical Clinic
Dr. Natkin is a Doctor of Osteopathic Medicine who completed orthopedic surgery training in Oregon before specializing in regenerative medicine, pain management, and hormone optimization. As the founder of R2 Medical Clinic, he has helped thousands of patients in the Denver area reclaim their vitality through evidence-based, personalized treatment. A Colorado resident since 1987 and avid cyclist, Dr. Natkin brings both clinical excellence and genuine passion for long-term wellness to every patient he serves.
Medical Disclaimer
This content is provided for informational purposes only and does not constitute medical advice, diagnosis, or treatment. Individual results may vary. Erectile dysfunction can be a symptom of underlying health conditions that require medical evaluation. Always consult with a qualified healthcare provider before beginning any treatment. The information presented here reflects the clinical experience of R2 Medical Clinic and is not intended to replace a professional medical consultation. InMode ApexRF is an FDA-cleared device; however, FDA clearance does not guarantee specific outcomes for individual patients.